Peptide Dosage Reference

Hexarelin Dosage

A potent hexapeptide GHRP studied for GH release via ghrelin-receptor pathways, with additional endocrine readouts.

Synthetic growth hormone secretagogue (GHRP)Half-life Short…Also called HEX, Examorelin, synthetic GHRP…4 verified citations

Hexarelin dosage calculator

Pre-loaded with a typical Hexarelin vial. Change any value to match what you actually have.

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Amounts reported in the literature

What published research and laboratory protocols actually document for Hexarelin. Where a compound has no single microgram figure, we say so rather than inventing one.

Reported amountFrequencyRouteWhere this figure comes from
35 mcg – 150 mcgsingle bolus exposures in study sessionsintravenousImbimbo et al. rising-dose IV study in healthy men
Published IV doses were 0.5, 1, and 2 mcg/kg. Absolute mcg above assumes roughly 70 kg body mass for schema display.
100 mcg – 200 mcgonce or twice daily in secondary protocol summariessubcutaneousCommonly cited subcutaneous research-protocol ranges
Secondary research summaries often discuss 100-200 mcg SC amounts; these are not standardized medical regimens.
Read this before using the table. Reference information only. The values below summarize amounts reported in published research literature and laboratory protocol discussions. They are not dosing recommendations, not medical advice, and not instructions for use in humans. All compounds referenced are for laboratory research use only and are not for human consumption.

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What Hexarelin is

Hexarelin is a synthetic six-amino-acid growth hormone-releasing peptide (GHRP) and ghrelin-mimetic secretagogue. In human and animal studies from the 1990s onward, it produced robust, dose-dependent GH release after intravenous or other parenteral administration, often with smaller concurrent rises in prolactin, ACTH, and cortisol.

Researchers use hexarelin as a benchmark GHS-R agonist when mapping pituitary responsiveness, aging-related GH decline, feedback inhibition by exogenous GH, and comparative potency versus GHRP-2, GHRP-6, or later secretagogues. Some preclinical literature also explores cardiovascular and non-endocrine actions, though the densest evidence base remains endocrine pharmacology.

Research-grade hexarelin is Research Use Only. It is not FDA-approved for human therapy and is not for human consumption. Reported mcg/kg and absolute mcg figures below are literature references only.

How it works

Hexarelin activates the growth hormone secretagogue receptor (GHS-R1a), the same receptor engaged by ghrelin. Pituitary and hypothalamic actions promote GH secretion and can synergize with GHRH-pathway input. Unlike pure GHRH analogs, GHRPs commonly influence additional axes at higher exposures, which is why prolactin and HPA-axis readouts appear in classic human dose-response papers.

Where it shows up in research

GH secretagogue pharmacology · pituitary stimulation testing models · aging and GH-axis responsiveness · GHRH and GHRP combination physiology · comparative GHS-R agonist research

Who studies it

Neuroendocrinology labs and GH-axis pharmacology groups are the core users. Historical clinical-research units also used hexarelin in controlled dose-response and repeated-administration studies in healthy volunteers and selected patient cohorts.

Storage & handling

Store lyophilized hexarelin cold and dry. After reconstitution, refrigerate, protect from light, and avoid unnecessary freeze-thaw cycles.

Commonly researched alongside

Hexarelin is classically studied with GHRH or long-acting GHRH analogs such as CJC-1295 because dual-receptor input can amplify GH output. Comparative designs versus ipamorelin or GHRP-2 are also common when the experimental goal is selectivity and side-axis activation profiling.

Hexarelin dosage questions

The questions people actually search for, answered plainly.

Human IV dose-response work used about 0.5-2 mcg/kg. Secondary subcutaneous protocol charts often cite roughly 100-200 mcg per exposure. These are reference values, not advice.

Classic literature describes hexarelin as a highly potent GH secretagogue, often comparable to or stronger than earlier GHRP-6 benchmarks depending on model and route.

No. Studies also report modest increases in prolactin, ACTH, and cortisol at effective GH-releasing exposures, which is part of its pharmacologic fingerprint.

No. It is RUO laboratory material, not an FDA-approved therapy, and not for human consumption.

Because repeated administration can attenuate the GH response over time. Desensitization and feedback are important experimental variables.

Yes. Many research discussions pair a GHRP/GHS-R agonist with a GHRH analog to examine complementary GH-axis inputs.

Research suppliers commonly offer 2 mg or 5 mg lyophilized vials for reconstitution into working solutions.

Research citations

Primary literature on Hexarelin. Open access where available.

Every citation above was programmatically checked against the NCBI PubMed database. Titles shown are the official indexed titles, not paraphrases.

Other dosage references

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